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BMCBI
2004
141views more  BMCBI 2004»
13 years 4 months ago
Estimates of statistical significance for comparison of individual positions in multiple sequence alignments
Background: Profile-based analysis of multiple sequence alignments (MSA) allows for accurate comparison of protein families. Here, we address the problems of detecting statistical...
Ruslan Sadreyev, Nick V. Grishin
RECOMB
2003
Springer
14 years 5 months ago
A multi-expert system for the automatic detection of protein domains from sequence information
We describe a novel method for detecting the domain structure of a protein from sequence information alone. The method is based on analyzing multiple sequence alignments that are ...
Niranjan Nagarajan, Golan Yona
BMCBI
2005
125views more  BMCBI 2005»
13 years 4 months ago
Multiple sequence alignments of partially coding nucleic acid sequences
Background: High quality sequence alignments of RNA and DNA sequences are an important prerequisite for the comparative analysis of genomic sequence data. Nucleic acid sequences, ...
Roman R. Stocsits, Ivo L. Hofacker, Claudia Fried,...
EVOW
2010
Springer
13 years 8 months ago
Improving Multi-Relief for Detecting Specificity Residues from Multiple Sequence Alignments
A challenging problem in bioinformatics is the detection of residues that account for protein function specificity, not only in order to gain deeper insight in the nature of functi...
Elena Marchiori
CIKM
2008
Springer
13 years 6 months ago
Pairwise statistical significance of local sequence alignment using multiple parameter sets
Background: Accurate estimation of statistical significance of a pairwise alignment is an important problem in sequence comparison. Recently, a comparative study of pairwise stati...
Ankit Agrawal, Xiaoqiu Huang