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» Extending the Hardness of RNA Secondary Structure Comparison
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JCB
2007
94views more  JCB 2007»
13 years 5 months ago
Locality and Gaps in RNA Comparison
Locality is an important and well-studied notion in comparative analysis of biological sequences. Similarly, taking into account affine gap penalties when calculating biological ...
Rolf Backofen, Shihyen Chen, Danny Hermelin, Gad M...
BIB
2011
13 years 24 days ago
Mutational analysis in RNAs: comparing programs for RNA deleterious mutation prediction
Programs for RNA mutational analysis that are structure-based and rely on secondary structure prediction have been developed and expanded in the past several years. They can be us...
Danny Barash, Alexander Churkin
BMCBI
2007
114views more  BMCBI 2007»
13 years 5 months ago
Large scale statistical inference of signaling pathways from RNAi and microarray data
Background: The advent of RNA interference techniques enables the selective silencing of biologically interesting genes in an efficient way. In combination with DNA microarray tec...
Holger Fröhlich, Mark Fellmann, Holger Sü...
BMCBI
2004
146views more  BMCBI 2004»
13 years 5 months ago
The InDeVal insertion/deletion evaluation tool: a program for finding target regions in DNA sequences and for aiding in sequence
Background: The program InDeVal was originally developed to help researchers find known regions of insertion/deletion activity (with the exception of isolated single-base indels) ...
Sierra D. Stoneberg Holt, Jason A. Holt
BMCBI
2005
125views more  BMCBI 2005»
13 years 5 months ago
Multiple sequence alignments of partially coding nucleic acid sequences
Background: High quality sequence alignments of RNA and DNA sequences are an important prerequisite for the comparative analysis of genomic sequence data. Nucleic acid sequences, ...
Roman R. Stocsits, Ivo L. Hofacker, Claudia Fried,...