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» Extensions to gene set enrichment
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BMCBI
2008
155views more  BMCBI 2008»
13 years 5 months ago
Extending pathways based on gene lists using InterPro domain signatures
Background: High-throughput technologies like functional screens and gene expression analysis produce extended lists of candidate genes. Gene-Set Enrichment Analysis is a commonly...
Florian Hahne, Alexander Mehrle, Dorit Arlt, Annem...
BMCBI
2010
167views more  BMCBI 2010»
13 years 5 months ago
Bi-directional gene set enrichment and canonical correlation analysis identify key diet-sensitive pathways and biomarkers of met
Background: Currently, a number of bioinformatics methods are available to generate appropriate lists of genes from a microarray experiment. While these lists represent an accurat...
Melissa J. Morine, Jolene McMonagle, Sinead Toomey...
WOB
2007
13 years 6 months ago
Gene Set Enrichment Analysis Using Non-parametric Scores
Abstract. Gene Set Enrichment Analysis (GSEA) is a well-known technique used for studying groups of functionally related genes and their correlation with phenotype. This method cre...
Ariel E. Bayá, Mónica G. Larese, Pab...
BMCBI
2008
129views more  BMCBI 2008»
13 years 5 months ago
Gene set enrichment analysis for non-monotone association and multiple experimental categories
Background: Recently, microarray data analyses using functional pathway information, e.g., gene set enrichment analysis (GSEA) and significance analysis of function and expression...
Rongheng Lin, Shuangshuang Dai, Richard D. Irwin, ...
BMCBI
2010
112views more  BMCBI 2010»
13 years 5 months ago
PhenoFam-gene set enrichment analysis through protein structural information
Background: With the current technological advances in high-throughput biology, the necessity to develop tools that help to analyse the massive amount of data being generated is e...
Maciej Paszkowski-Rogacz, Mikolaj Slabicki, M. Ter...