27 search results - page 4 / 6 » FACT: Functional annotation transfer between proteins with s... |
BMCBI
2007
13 years 5 months ago
2007
Background: Unsupervised annotation of proteins by software pipelines suffers from very high error rates. Spurious functional assignments are usually caused by unwarranted homolog...
NAR
2007
13 years 4 months ago
2007
Phylogenomic analysis addresses the limitations of function prediction based on annotation transfer, and has been shown to enable the highest accuracy in prediction of protein mol...
BMCBI
2005
13 years 5 months ago
2005
Background: Profile hidden Markov model (HMM) techniques are among the most powerful methods for protein homology detection. Yet, the critical features for successful modelling ar...
CBMS
2008
IEEE
13 years 11 months ago
2008
IEEE
We propose a new method for measuring the semantic similarity of genes based on path length between their annotation terms in the Gene Ontology. Our method applies an exponential ...
BMCBI
2007
13 years 5 months ago
2007
Background: Since many of the new protein structures delivered by high-throughput processes do not have any known function, there is a need for structure-based prediction of prote...