6 search results - page 1 / 2 » False occurrences of functional motifs in protein sequences ... |
BMCBI
2007
13 years 5 months ago
2007
Background: False occurrences of functional motifs in protein sequences can be considered as random events due solely to the sequence composition of a proteome. Here we use a nume...
BMCBI
2007
13 years 4 months ago
2007
Background: We performed an exhaustive search for local structural similarities in an ensemble of non-redundant protein functional sites. With the purpose of finding new examples ...
BMCBI
2007
13 years 4 months ago
2007
Background: Protein remote homology detection is a central problem in computational biology. Most recent methods train support vector machines to discriminate between related and ...
WABI
2010
Springer
13 years 3 months ago
2010
Springer
Quantification of selective pressures on regulatory sequences is a central question in studying the evolution of gene regulatory networks. Previous methods focus primarily on sing...
ICASSP
2007
IEEE
13 years 11 months ago
2007
IEEE
There are currently a large number of ‘‘orphan’’ G-protein-coupled receptors (GPCRs) whose endogenous ligands (peptide hormones) are unknown. Identification of these pepti...