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» Family specific rates of protein evolution
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BIOINFORMATICS
2006
95views more  BIOINFORMATICS 2006»
13 years 5 months ago
Family specific rates of protein evolution
: Amino acid changing mutations in proteins are contstrained by purifying selection and accumulate at different rates. We estimate evolutionary rates on multiple alignments of euka...
Hannes Luz, Martin Vingron
BMCBI
2007
116views more  BMCBI 2007»
13 years 4 months ago
Linear array of conserved sequence motifs to discriminate protein subfamilies: study on pyridine nucleotide-disulfide reductases
Background: The pyridine nucleotide disulfide reductase (PNDR) is a large and heterogeneous protein family divided into two classes (I and II), which reflect the divergent evoluti...
César L. Avila, Viviana A. Rapisarda, Ricar...
BMCBI
2006
107views more  BMCBI 2006»
13 years 5 months ago
A reinforced merging methodology for mapping unique peptide motifs in members of protein families
Background: Members of a protein family often have highly conserved sequences; most of these sequences carry identical biological functions and possess similar three-dimensional (...
Hao-Teng Chang, Tun-Wen Pai, Tan-Chi Fan, Bo-Han S...
BMCBI
2007
109views more  BMCBI 2007»
13 years 5 months ago
Towards a comprehensive structural coverage of completed genomes: a structural genomics viewpoint
Background: Structural genomics initiatives were established with the aim of solving protein structures on a large-scale. For many initiatives, such as the Protein Structure Initi...
Russell L. Marsden, Tony A. Lewis, Christine A. Or...
BMCBI
2005
97views more  BMCBI 2005»
13 years 4 months ago
Clustering the annotation space of proteins
Background: Current protein clustering methods rely on either sequence or functional similarities between proteins, thereby limiting inferences to one of these areas. Results: Her...
Victor Kunin, Christos A. Ouzounis