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» Fast Structured Motif Search in DNA Sequences
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BIRD
2008
Springer
177views Bioinformatics» more  BIRD 2008»
13 years 6 months ago
Fast Structured Motif Search in DNA Sequences
We study the problem of structured motif search in DNA sequences. This is a fundamental task in bioinformatics which contributes to better understanding of genome characteristics a...
Mihail Halachev, Nematollaah Shiri
CPM
2007
Springer
222views Combinatorics» more  CPM 2007»
13 years 11 months ago
Computing Exact p-Value for Structured Motif
Extracting motifs from a set of DNA sequences is important in computational biology. Occurrence probability is a common used statistics to evaluate the statistical significance of...
Jing Zhang, Xi Chen, Ming Li
BMCBI
2007
190views more  BMCBI 2007»
13 years 5 months ago
Discriminative motif discovery in DNA and protein sequences using the DEME algorithm
Background: Motif discovery aims to detect short, highly conserved patterns in a collection of unaligned DNA or protein sequences. Discriminative motif finding algorithms aim to i...
Emma Redhead, Timothy L. Bailey
BMCBI
2006
108views more  BMCBI 2006»
13 years 4 months ago
Promoter prediction and annotation of microbial genomes based on DNA sequence and structural responses to superhelical stress
Background: In our previous studies, we found that the sites in prokaryotic genomes which are most susceptible to duplex destabilization under the negative superhelical stresses t...
Huiquan Wang, Craig J. Benham
BMCBI
2006
103views more  BMCBI 2006»
13 years 4 months ago
Cis-motifs upstream of the transcription and translation initiation sites are effectively revealed by their positional disequili
Background: The discovery of cis-regulatory motifs still remains a challenging task even though the number of sequenced genomes is constantly growing. Computational analyses using...
Kenneth W. Berendzen, Kurt Stüber, Klaus Hart...