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BMCBI
2010
190views more  BMCBI 2010»
13 years 5 months ago
APIS: accurate prediction of hot spots in protein interfaces by combining protrusion index with solvent accessibility
Background: It is well known that most of the binding free energy of protein interaction is contributed by a few key hot spot residues. These residues are crucial for understandin...
Jun-Feng Xia, Xing-Ming Zhao, Jiangning Song, De-S...
BMCBI
2004
114views more  BMCBI 2004»
13 years 5 months ago
Profiled support vector machines for antisense oligonucleotide efficacy prediction
Background: This paper presents the use of Support Vector Machines (SVMs) for prediction and analysis of antisense oligonucleotide (AO) efficacy. The collected database comprises ...
Gustavo Camps-Valls, Alistair M. Chalk, Antonio J....
ISMB
2008
13 years 8 months ago
Classification of arrayCGH data using fused SVM
Motivation: Array-based comparative genomic hybridization (arrayCGH) has recently become a popular tool to identify DNA copy number variations along the genome. These profiles are...
Franck Rapaport, Emmanuel Barillot, Jean-Philippe ...
CIDM
2007
IEEE
13 years 12 months ago
Mining Subspace Correlations
— In recent applications of clustering such as gene expression microarray analysis, collaborative filtering, and web mining, object similarity is no longer measured by physical ...
Rave Harpaz, Robert M. Haralick
BMCBI
2007
125views more  BMCBI 2007»
13 years 5 months ago
Identification of discriminative characteristics for clusters from biologic data with InforBIO software
Background: There are a number of different methods for generation of trees and algorithms for phylogenetic analysis in the study of bacterial taxonomy. Genotypic information, suc...
Naoto Tanaka, Masataka Uchino, Satoru Miyazaki, Hi...