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APBC
2004
13 years 6 months ago
Filtering of Ineffective siRNAs and Improved siRNA Design Tool
Prudence W. H. Wong, Tak Wah Lam, Y. C. Mui, Siu-M...
BMCBI
2006
123views more  BMCBI 2006»
13 years 5 months ago
Computational models with thermodynamic and composition features improve siRNA design
Background: Small interfering RNAs (siRNAs) have become an important tool in cell and molecular biology. Reliable design of siRNA molecules is essential for the needs of large fun...
Svetlana A. Shabalina, Alexey N. Spiridonov, Aleks...
SCFBM
2008
87views more  SCFBM 2008»
13 years 4 months ago
Analysis by siRNA_profile program displays novel thermodynamic characteristics of highly functional siRNA molecules
Objective: Here we report the improved results of a new siRNA design program and analysis tool called siRNA_profile that reveals an additional criterion for bioinformatic search o...
Pirkko Muhonen, Ranga N. Parthasarathy, Anthony J....