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» Finding anchors for genomic sequence comparison
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BMCBI
2005
109views more  BMCBI 2005»
13 years 4 months ago
Genome comparison without alignment using shortest unique substrings
Background: Sequence comparison by alignment is a fundamental tool of molecular biology. In this paper we show how a number of sequence comparison tasks, including the detection o...
Bernhard Haubold, Nora Pierstorff, Friedrich M&oum...
BMCBI
2006
92views more  BMCBI 2006»
13 years 4 months ago
Similarity-based gene detection: using COGs to find evolutionarily-conserved ORFs
Background: Experimental verification of gene products has not kept pace with the rapid growth of microbial sequence information. However, existing annotations of gene locations c...
Bradford C. Powell, Clyde A. Hutchison III
BMCBI
2008
99views more  BMCBI 2008»
13 years 4 months ago
Multiple organism algorithm for finding ultraconserved elements
Background: Ultraconserved elements are nucleotide or protein sequences with 100% identity (no mismatches, insertions, or deletions) in the same organism or between two or more or...
Scott Christley, Neil F. Lobo, Gregory R. Madey
RECOMB
2004
Springer
14 years 5 months ago
Chromosomal breakpoint re-use in the inference of genome sequence rearrangement
In order to apply gene-order rearrangement algorithms to the comparison of genome sequences, Pevzner and Tesler [9] bypass gene finding and ortholog identification, and use the or...
David Sankoff, Phil Trinh
BMCBI
2006
122views more  BMCBI 2006»
13 years 4 months ago
Genome comparison using Gene Ontology (GO) with statistical testing
Background: Automated comparison of complete sets of genes encoded in two genomes can provide insight on the genetic basis of differences in biological traits between species. Gen...
Zhaotao Cai, Xizeng Mao, Songgang Li, Liping Wei