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» Finding motifs in the twilight zone
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BIOCOMP
2009
13 years 6 months ago
Improving Remote Homology Detection Using Sequence Properties and Position Specific Scoring Matrices
Current biological sequence comparison tools frequently fail to recognize matches between homologs when sequence similarity is below the twilight zone of less than 25% sequence id...
Gina Cooper, Michael L. Raymer
BMCBI
2010
189views more  BMCBI 2010»
13 years 5 months ago
High quality protein sequence alignment by combining structural profile prediction and profile alignment using SABERTOOTH
Background: Protein alignments are an essential tool for many bioinformatics analyses. While sequence alignments are accurate for proteins of high sequence similarity, they become...
Florian Teichert, Jonas Minning, Ugo Bastolla, Mar...