Over the last two decades a large number of algorithms has been developed for regulatory motif finding. Here we show how many of these algorithms, especially those that model bind...
Background: Algorithms that locate evolutionarily conserved sequences have become powerful tools for finding functional DNA elements, including transcription factor binding sites;...
Background: This work addresses the problem of detecting conserved transcription factor binding sites and in general regulatory regions through the analysis of sequences from homo...
KIM, JIHYE. Mining of Cis-Regulatory Motifs Associated with Tissue-Specific Alternative Splicing. (Under the direction of Steffen Heber). Alternative splicing (AS) is an important...
Jihye Kim, Sihui Zhao, Brian E. Howard, Steffen He...
Background: Discovering approximately repeated patterns, or motifs, in biological sequences is an important and widely-studied problem in computational molecular biology. Most fre...