8 search results - page 1 / 2 » Fine-tuning structural RNA alignments in the twilight zone |
BMCBI
2010
13 years 5 months ago
2010
Background: A widely used method to find conserved secondary structure in RNA is to first construct a multiple sequence alignment, and then fold the alignment, optimizing a score ...
ALMOB
2006
13 years 5 months ago
2006
Background: The performance of alignment programs is traditionally tested on sets of protein sequences, of which a reference alignment is known. Conclusions drawn from such protei...
BMCBI
2010
13 years 5 months ago
2010
Background: In recent years, the number of available RNA structures has rapidly grown reflecting the increased interest on RNA biology. Similarly to the studies carried out two de...
CIBCB
2006
IEEE
13 years 11 months ago
2006
IEEE
– Protein structure prediction is one of the core research areas in bioinformatics. This paper addresses the protein secondary structure prediction problem for the twilight zone ...
BMCBI
2010
13 years 5 months ago
2010
Background: Protein alignments are an essential tool for many bioinformatics analyses. While sequence alignments are accurate for proteins of high sequence similarity, they become...