13 search results - page 2 / 3 » Framework for Identifying Common Aberrations in DNA Copy Num... |
BMCBI
2010
13 years 5 months ago
2010
Background: Cancer is a complex disease where various types of molecular aberrations drive the development and progression of malignancies. Large-scale screenings of multiple type...
BMCBI
2007
13 years 5 months ago
2007
Background: The sequencing of many genomes and tiling arrays consisting of millions of DNA segments spanning entire genomes have made high-resolution copy number analysis possible...
BMCBI
2011
12 years 8 months ago
2011
Background: Copy number aberrations (CNAs) are an important molecular signature in cancer initiation, development, and progression. However, these aberrations span a wide range of...
BMCBI
2011
12 years 8 months ago
2011
Background: Copy number variants (CNVs), including deletions, amplifications, and other rearrangements, are common in human and cancer genomes. Copy number data from array compara...
BMCBI
2005
13 years 5 months ago
2005
Background: Microarray-CGH experiments are used to detect and map chromosomal imbalances, by hybridizing targets of genomic DNA from a test and a reference sample to sequences imm...