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BMCBI
2008
90views more  BMCBI 2008»
13 years 5 months ago
Genome-scale study of the importance of binding site context for transcription factor binding and gene regulation
Background: The rate of mRNA transcription is controlled by transcription factors that bind to specific DNA motifs in promoter regions upstream of protein coding genes. Recent res...
Jakub Orzechowski Westholm, Feifei Xu, Hans Ronne,...
BMCBI
2004
207views more  BMCBI 2004»
13 years 5 months ago
Computational identification of transcription factor binding sites by functional analysis of sets of genes sharing overrep-resen
Background: Transcriptional regulation is a key mechanism in the functioning of the cell, and is mostly effected through transcription factors binding to specific recognition moti...
Davide Corà, Ferdinando Di Cunto, Paolo Pro...
BMCBI
2010
134views more  BMCBI 2010»
13 years 5 months ago
Localizing triplet periodicity in DNA and cDNA sequences
Background: The protein-coding regions (coding exons) of a DNA sequence exhibit a triplet periodicity (TP) due to fact that coding exons contain a series of three nucleotide codon...
Liya Wang, Lincoln D. Stein
BMCBI
2006
155views more  BMCBI 2006»
13 years 5 months ago
Analysis of promoter regions of co-expressed genes identified by microarray analysis
Background: The use of global gene expression profiling to identify sets of genes with similar expression patterns is rapidly becoming a widespread approach for understanding biol...
Srinivas Veerla, Mattias Höglund
RECOMB
2010
Springer
13 years 7 months ago
Leveraging Sequence Classification by Taxonomy-Based Multitask Learning
In this work we consider an inference task that biologists are very good at: deciphering biological processes by bringing together knowledge that has been obtained by experiments u...
Christian Widmer, Jose Leiva, Yasemin Altun, Gunna...