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» Functional annotation by identification of local surface sim...
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BMCBI
2010
131views more  BMCBI 2010»
13 years 4 months ago
FACT: Functional annotation transfer between proteins with similar feature architectures
Background: The increasing number of sequenced genomes provides the basis for exploring the genetic and functional diversity within the tree of life. Only a tiny fraction of the e...
Tina Koestler, Arndt von Haeseler, Ingo Ebersberge...
FPL
2004
Springer
109views Hardware» more  FPL 2004»
13 years 10 months ago
Hardware Accelerated Novel Protein Identification
The proteins in living organisms perform almost every significant function that governs life. A protein's functionality depends upon its physical structure, which depends on i...
Anish Alex, Jonathan Rose, Ruth Isserlin-Weinberge...
BMCBI
2006
127views more  BMCBI 2006»
13 years 4 months ago
Using local gene expression similarities to discover regulatory binding site modules
Background: We present an approach designed to identify gene regulation patterns using sequence and expression data collected for Saccharomyces cerevisae. Our main goal is to rela...
Bartek Wilczynski, Torgeir R. Hvidsten, Andriy Kry...
NAR
2011
207views Computer Vision» more  NAR 2011»
12 years 7 months ago
PSORTdb - an expanded, auto-updated, user-friendly protein subcellular localization database for Bacteria and Archaea
The subcellular localization (SCL) of a microbial protein provides clues about its function, its suitability as a drug, vaccine or diagnostic target and aids experimental design. ...
Nancy Y. Yu, Matthew R. Laird, Cory Spencer, Fiona...
BMCBI
2005
121views more  BMCBI 2005»
13 years 4 months ago
Automated methods of predicting the function of biological sequences using GO and BLAST
Background: With the exponential increase in genomic sequence data there is a need to develop automated approaches to deducing the biological functions of novel sequences with hig...
Craig E. Jones, Ute Baumann, Alfred L. Brown