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» Functional topology in a network of protein interactions
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BIOINFORMATICS
2004
43views more  BIOINFORMATICS 2004»
13 years 4 months ago
Functional topology in a network of protein interactions
Natasa Przulj, Dennis A. Wigle, Igor Jurisica
LION
2009
Springer
112views Optimization» more  LION 2009»
13 years 11 months ago
A Graph-Based Semi-supervised Algorithm for Protein Function Prediction from Interaction Maps
Abstract. Protein function prediction represents a fundamental challenge in bioinformatics. The increasing availability of proteomics network data has enabled the development of se...
Valerio Freschi
CSB
2005
IEEE
110views Bioinformatics» more  CSB 2005»
13 years 10 months ago
A Topological Measurement for Weighted Protein Interaction Network
High-throughput methods for detecting protein-protein interactions (PPI) have given researchers an initial global picture of protein interactions on a genomic scale. The usefulnes...
Pengjun Pei, Aidong Zhang
BMCBI
2010
179views more  BMCBI 2010»
13 years 4 months ago
A semi-supervised learning approach to predict synthetic genetic interactions by combining functional and topological properties
Background: Genetic interaction profiles are highly informative and helpful for understanding the functional linkages between genes, and therefore have been extensively exploited ...
Zhuhong You, Zheng Yin, Kyungsook Han, De-Shuang H...
BIBE
2005
IEEE
154views Bioinformatics» more  BIBE 2005»
13 years 10 months ago
Effective Pre-Processing Strategies for Functional Clustering of a Protein-Protein Interactions Network
In this article we present novel preprocessing techniques, based on topological measures of the network, to identify clusters of proteins from Protein-protein interaction (PPI) ne...
Duygu Ucar, Srinivasan Parthasarathy, Sitaram Asur...