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    » GASP: Gapped Ancestral Sequence Prediction for proteins
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    BMCBI
    2011
    187views Artificial Intelligence» more  BMCBI 2011»
    Detection of Lineage-Specific Evolutionary Changes among Primate Species
    12 years 9 months ago
    Detection of Lineage-Specific Evolutionary Changes among Primate Species
    Download  www.biomedcentral.com
    Background: Comparison of the human genome with other primates offers the opportunity to detect evolutionary events that created the diverse phenotypes among the primate species. ...
    Mihaela Pertea, Geo Pertea, Steven L. Salzberg
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    RECOMB
    2005
    Springer
    76views Computational Biology» more  RECOMB 2005»
    Very Low Power to Detect Asymmetric Divergence of Duplicated Genes
    14 years 5 months ago
    Very Low Power to Detect Asymmetric Divergence of Duplicated Genes
    Download  cbio.uct.ac.za
    Abstract. Asymmetric functional divergence of paralogues is a key aspect of the traditional model of evolution following duplication. If one gene continues to perform the ancestral...
    Cathal Seoighe, Konrad Scheffler
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    BMCBI
    2007
    127views more  BMCBI 2007»
    CORRIE: enzyme sequence annotation with confidence estimates
    13 years 5 months ago
    CORRIE: enzyme sequence annotation with confidence estimates
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    Using a previously developed automated method for enzyme annotation, we report the reannotation of the ENZYME database and the analysis of local error rates per class. In control ...
    Benjamin Audit, Emmanuel D. Levy, Walter R. Gilks,...
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    BMCBI
    2004
    208views more  BMCBI 2004»
    Using 3D Hidden Markov Models that explicitly represent spatial coordinates to model and compare protein structures
    13 years 5 months ago
    Using 3D Hidden Markov Models that explicitly represent spatial coordinates to model and compare protein structures
    Download  www.biomedcentral.com
    Background: Hidden Markov Models (HMMs) have proven very useful in computational biology for such applications as sequence pattern matching, gene-finding, and structure prediction...
    Vadim Alexandrov, Mark Gerstein
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    BMCBI
    2010
    151views more  BMCBI 2010»
    Classification of G-protein coupled receptors based on support vector machine with maximum relevance minimum redundancy and gene
    13 years 5 months ago
    Classification of G-protein coupled receptors based on support vector machine with maximum relevance minimum redundancy and gene
    Download  www.biomedcentral.com
    Background: Because a priori knowledge about function of G protein-coupled receptors (GPCRs) can provide useful information to pharmaceutical research, the determination of their ...
    Zhanchao Li, Xuan Zhou, Zong Dai, Xiaoyong Zou
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