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BMCBI
2008
124views more  BMCBI 2008»
13 years 5 months ago
A relation based measure of semantic similarity for Gene Ontology annotations
Background: Various measures of semantic similarity of terms in bio-ontologies such as the Gene Ontology (GO) have been used to compare gene products. Such measures of similarity ...
Brendan Sheehan, Aaron J. Quigley, Benoit Gaudin, ...
WABI
2005
Springer
179views Bioinformatics» more  WABI 2005»
13 years 10 months ago
Spectral Clustering Gene Ontology Terms to Group Genes by Function
Abstract. With the invention of biotechnological high throughput methods like DNA microarrays, biologists are capable of producing huge amounts of data. During the analysis of such...
Nora Speer, Christian Spieth, Andreas Zell
JBCB
2010
138views more  JBCB 2010»
12 years 11 months ago
Hierarchical Classification of Gene Ontology Terms Using the Gostruct Method
Protein function prediction is an active area of research in bioinformatics. And yet, transfer of annotation on the basis of sequence or structural similarity remains widely used ...
Artem Sokolov, Asa Ben-Hur
CISIS
2010
IEEE
13 years 11 months ago
Gene Ontology Rewritten for Computing Gene Functional Similarity
Abstract—Discovery biological organisation of the cell in modules network is a challenging task. Currently, approaches based on a controlled vocabulary, as Gene Ontology, to iden...
Alessia Visconti, Francesca Cordero, Marco Botta, ...
ICASSP
2008
IEEE
13 years 11 months ago
Probabilistic framework for gene expression clustering validation based on gene ontology and graph theory
Based on the correlation between expression and ontologydriven gene similarity, we incorporate functional annotations into gene expression clustering validation. A probabilistic f...
Yinyin Yuan, Chang-Tsun Li