Background: Various measures of semantic similarity of terms in bio-ontologies such as the Gene Ontology (GO) have been used to compare gene products. Such measures of similarity ...
Brendan Sheehan, Aaron J. Quigley, Benoit Gaudin, ...
Abstract. With the invention of biotechnological high throughput methods like DNA microarrays, biologists are capable of producing huge amounts of data. During the analysis of such...
Protein function prediction is an active area of research in bioinformatics. And yet, transfer of annotation on the basis of sequence or structural similarity remains widely used ...
Abstract—Discovery biological organisation of the cell in modules network is a challenging task. Currently, approaches based on a controlled vocabulary, as Gene Ontology, to iden...
Alessia Visconti, Francesca Cordero, Marco Botta, ...
Based on the correlation between expression and ontologydriven gene similarity, we incorporate functional annotations into gene expression clustering validation. A probabilistic f...