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BMCBI
2005
201views more  BMCBI 2005»
13 years 5 months ago
Principal component analysis for predicting transcription-factor binding motifs from array-derived data
Background: The responses to interleukin 1 (IL-1) in human chondrocytes constitute a complex regulatory mechanism, where multiple transcription factors interact combinatorially to...
Yunlong Liu, Matthew P. Vincenti, Hiroki Yokota
BMCBI
2007
123views more  BMCBI 2007»
13 years 5 months ago
Heritable clustering and pathway discovery in breast cancer integrating epigenetic and phenotypic data
Background: In order to recapitulate tumor progression pathways using epigenetic data, we developed novel clustering and pathway reconstruction algorithms, collectively referred t...
Zailong Wang, Pearlly Yan, Dustin P. Potter, Chari...
PPOPP
2006
ACM
13 years 11 months ago
Performance characterization of molecular dynamics techniques for biomolecular simulations
Large-scale simulations and computational modeling using molecular dynamics (MD) continues to make significant impacts in the field of biology. It is well known that simulations...
Sadaf R. Alam, Jeffrey S. Vetter, Pratul K. Agarwa...
BMCBI
2008
160views more  BMCBI 2008»
13 years 5 months ago
Feature selection environment for genomic applications
Background: Feature selection is a pattern recognition approach to choose important variables according to some criteria in order to distinguish or explain certain phenomena (i.e....
Fabrício Martins Lopes, David Correa Martin...
BICOB
2009
Springer
14 years 3 days ago
Assembly of Large Genomes from Paired Short Reads
The de novo assembly of genomes from high-throughput short reads is an active area of research. Several promising methods have been recently developed, with applicability mainly re...
Benjamin G. Jackson, Patrick S. Schnable, Srinivas...