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BMCBI
2006
143views more  BMCBI 2006»
13 years 5 months ago
IsoSVM - Distinguishing isoforms and paralogs on the protein level
Background: Recent progress in cDNA and EST sequencing is yielding a deluge of sequence data. Like database search results and proteome databases, this data gives rise to inferred...
Michael Spitzer, Stefan Lorkowski, Paul Cullen, Al...
BMCBI
2007
166views more  BMCBI 2007»
13 years 5 months ago
PathFinder: mining signal transduction pathway segments from protein-protein interaction networks
Background: A Signal transduction pathway is the chain of processes by which a cell converts an extracellular signal into a response. In most unicellular organisms, the number of ...
Gürkan Bebek, Jiong Yang
NAR
2007
95views more  NAR 2007»
13 years 4 months ago
VisANT 3.0: new modules for pathway visualization, editing, prediction and construction
With the integration of the KEGG and Predictome databases as well as two search engines for coexpressed genes/proteins using data sets obtained from the Stanford Microarray Databa...
Zhenjun Hu, David M. Ng, Takuji Yamada, Chunnuan C...
BMCBI
2007
148views more  BMCBI 2007»
13 years 5 months ago
fREDUCE: Detection of degenerate regulatory elements using correlation with expression
Background: The precision of transcriptional regulation is made possible by the specificity of physical interactions between transcription factors and their cognate binding sites ...
Randy Z. Wu, Christina Chaivorapol, Jiashun Zheng,...
BMCBI
2006
157views more  BMCBI 2006»
13 years 5 months ago
Comparison of protein interaction networks reveals species conservation and divergence
Background: Recent progresses in high-throughput proteomics have provided us with a first chance to characterize protein interaction networks (PINs), but also raised new challenge...
Zhi Liang, Meng Xu, Maikun Teng, Liwen Niu