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» Generalized Composite Motif Discovery
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CIBCB
2006
IEEE
13 years 11 months ago
Motif Evaluation by Leave-one-out Scoring
Abstract— We propose a new method for collecting information on regulatory elements found by any motif discovery program. We suggest that combining the results of n leave-oneout ...
Audrey Girouard, Noah W. Smith, Donna K. Slonim
BMCBI
2008
99views more  BMCBI 2008»
13 years 5 months ago
NestedMICA as an ab initio protein motif discovery tool
Background: Discovering overrepresented patterns in amino acid sequences is an important step in protein functional element identification. We adapted and extended NestedMICA, an ...
Mutlu Dogruel, Thomas A. Down, Tim J. P. Hubbard
ISMB
1993
13 years 6 months ago
Representation for Discovery of Protein Motifs
There are several dimensions and levels of complexity in which information on protein motifs may be available. For example, onedimensional sequence motifs may be associated with s...
Darrell Conklin, Suzanne Fortier, Janice I. Glasgo...
BMCBI
2002
128views more  BMCBI 2002»
13 years 5 months ago
Correlating overrepresented upstream motifs to gene expression: a computational approach to regulatory element discovery in euka
Background: Gene regulation in eukaryotes is mainly effected through transcription factors binding to rather short recognition motifs generally located upstream of the coding regi...
Michele Caselle, Ferdinando Di Cunto, Paolo Prover...
BMCBI
2007
100views more  BMCBI 2007»
13 years 5 months ago
Discovering structural motifs using a structural alphabet: Application to magnesium-binding sites
Background: For many metalloproteins, sequence motifs characteristic of metal-binding sites have not been found or are so short that they would not be expected to be metal-specifi...
Minko Dudev, Carmay Lim