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» Generation From Under - And Overspecified Structures
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CSB
2003
IEEE
130views Bioinformatics» more  CSB 2003»
13 years 10 months ago
A Computational Approach to Reconstructing Gene Regulatory Networks
Reverse-engineering of gene networks using linear models often results in an underdetermined system because of excessive unknown parameters. In addition, the practical utility of ...
Xutao Deng, Hesham H. Ali
AAAI
2010
13 years 6 months ago
A Two-Dimensional Topic-Aspect Model for Discovering Multi-Faceted Topics
This paper presents the Topic-Aspect Model (TAM), a Bayesian mixture model which jointly discovers topics and aspects. We broadly define an aspect of a document as a characteristi...
Michael Paul, Roxana Girju
CIDR
2009
119views Algorithms» more  CIDR 2009»
13 years 6 months ago
DBMSs Should Talk Back Too
Natural language user interfaces to database systems have been studied for several decades now. They have mainly focused on parsing and interpreting natural language queries to ge...
Alkis Simitsis, Yannis E. Ioannidis
BMCBI
2005
95views more  BMCBI 2005»
13 years 5 months ago
Commensurate distances and similar motifs in genetic congruence and protein interaction networks in yeast
Background: In a genetic interaction, the phenotype of a double mutant differs from the combined phenotypes of the underlying single mutants. When the single mutants have no growt...
Ping Ye, Brian D. Peyser, Forrest A. Spencer, Joel...
BMCBI
2004
146views more  BMCBI 2004»
13 years 5 months ago
Multivariate search for differentially expressed gene combinations
Background: To identify differentially expressed genes, it is standard practice to test a twosample hypothesis for each gene with a proper adjustment for multiple testing. Such te...
Yuanhui Xiao, Robert D. Frisina, Alexander Gordon,...