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» Genome Alignments Using MPI-LAGAN
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WABI
2007
Springer
13 years 12 months ago
Shotgun Protein Sequencing
Although snake venom proteins have been proven instrumental in the design of blood clotting and cytostatic breast cancer drugs, the main method in use to sequence these unknown pr...
Pavel A. Pevzner
DIS
2005
Springer
13 years 11 months ago
The Arrowsmith Project: 2005 Status Report
In the 1980s, Don Swanson proposed the concept of “undiscovered public knowledge,” and published several examples in which two disparate literatures (i.e., sets of articles hav...
Neil R. Smalheiser
BMCBI
2007
111views more  BMCBI 2007»
13 years 5 months ago
Novel definition files for human GeneChips based on GeneAnnot
Background: Improvements in genome sequence annotation revealed discrepancies in the original probeset/gene assignment in Affymetrix microarray and the existence of differences be...
Francesco Ferrari, Stefania Bortoluzzi, Alessandro...
BMCBI
2005
152views more  BMCBI 2005»
13 years 5 months ago
Improved profile HMM performance by assessment of critical algorithmic features in SAM and HMMER
Background: Profile hidden Markov model (HMM) techniques are among the most powerful methods for protein homology detection. Yet, the critical features for successful modelling ar...
Markus Wistrand, Erik L. L. Sonnhammer
BMCBI
2005
73views more  BMCBI 2005»
13 years 5 months ago
Evaluation of Glycine max mRNA clusters
Background: Clustering the ESTs from a large dataset representing a single species is a convenient starting point for a number of investigations into gene discovery, genome evolut...
Ronald L. Frank, Fikret Erçal