59 search results - page 1 / 12 » Genome-scale study of the importance of binding site context... |
BMCBI
2008
13 years 5 months ago
2008
Background: The rate of mRNA transcription is controlled by transcription factors that bind to specific DNA motifs in promoter regions upstream of protein coding genes. Recent res...
BMCBI
2004
13 years 4 months ago
2004
Background: Transcriptional regulation is a key mechanism in the functioning of the cell, and is mostly effected through transcription factors binding to specific recognition moti...
BMCBI
2006
13 years 4 months ago
2006
Background: Discovery of precise specificity of transcription factors is an important step on the way to understanding the complex mechanisms of gene regulation in eukaryotes. Rec...
ISMB
2000
13 years 6 months ago
2000
Understanding the mechanismsthat determine the regulation of geneexpression is an important and challenging problem. A fundamental subproblem is to identify DNA-bindingsites for u...
BMCBI
2008
13 years 5 months ago
2008
Background: The identification of transcription factor binding sites is difficult since they are only a small number of nucleotides in size, resulting in large numbers of false po...