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BMCBI
2007
163views more  BMCBI 2007»
13 years 5 months ago
Use of genomic DNA control features and predicted operon structure in microarray data analysis: ArrayLeaRNA - a Bayesian approac
Background: Microarrays are widely used for the study of gene expression; however deciding on whether observed differences in expression are significant remains a challenge. Resul...
Carmen Pin, Mark Reuter
BMCBI
2007
167views more  BMCBI 2007»
13 years 5 months ago
A stochastic differential equation model for transcriptional regulatory networks
Background: This work explores the quantitative characteristics of the local transcriptional regulatory network based on the availability of time dependent gene expression data se...
Adriana Climescu-Haulica, Michelle D. Quirk
BMCBI
2005
79views more  BMCBI 2005»
13 years 5 months ago
Mathematical design of prokaryotic clone-based microarrays
Background: Clone-based microarrays, on which each spot represents a random genomic fragment, are a good alternative to open reading frame-based microarrays, especially for microo...
Bart Pieterse, Elisabeth J. Quirijns, Frank H. J. ...
BIBM
2010
IEEE
173views Bioinformatics» more  BIBM 2010»
13 years 2 months ago
Network-based identification of smoking-associated gene signature for lung cancer
This study presents a novel computational approach to identifying a smoking-associated gene signature. The methodology contains the following steps: 1) identifying genes significa...
Ying-Wooi Wan, Changchang Xiao, Nancy Lan Guo
BIOCOMP
2006
13 years 6 months ago
Marker Gene Selection Evaluation in Brain Tumor Patients Using Parallel Coordinates
Based on microarray gene expression datasets, many statistical methods have been proposed to locate the significant differentially expressed genes (marker genes) among different sa...
Atiq Islam, Khan M. Iftekharuddin, David J. Russom...