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» Genotype Error Detection Using Hidden Markov Models of Haplo...
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WABI
2007
Springer
13 years 11 months ago
Genotype Error Detection Using Hidden Markov Models of Haplotype Diversity
Justin Kennedy, Ion I. Mandoiu, Bogdan Pasaniuc
BMCBI
2008
138views more  BMCBI 2008»
13 years 5 months ago
Inference of haplotypic phase and missing genotypes in polyploid organisms and variable copy number genomic regions
Background: The power of haplotype-based methods for association studies, identification of regions under selection, and ancestral inference, is well-established for diploid organ...
Shu-Yi Su, Jonathan White, David J. Balding, Lachl...
WABI
2005
Springer
118views Bioinformatics» more  WABI 2005»
13 years 11 months ago
A Hidden Markov Technique for Haplotype Reconstruction
We give a new algorithm for the genotype phasing problem. Our solution is based on a hidden Markov model for haplotypes. The model has a uniform structure, unlike most solutions pr...
Pasi Rastas, Mikko Koivisto, Heikki Mannila, Esko ...
JCB
2006
123views more  JCB 2006»
13 years 5 months ago
Reconstructing Ancestral Haplotypes with a Dictionary Model
We propose a dictionary model for haplotypes. According to the model, a haplotype is constructed by randomly concatenating haplotype segments from a given dictionary of segments. ...
Kristin L. Ayers, Chiara Sabatti, Kenneth Lange
WABI
2007
Springer
110views Bioinformatics» more  WABI 2007»
13 years 11 months ago
Haplotype Inference Via Hierarchical Genotype Parsing
The within-species genetic variation due to recombinations leads to a mosaic-like structure of DNA. This structure can be modeled, e.g. by parsing sample sequences of current DNA w...
Pasi Rastas, Esko Ukkonen