The 1000 Genome project has made available a large number of single nucleotide polymorphisms (SNPs) for genome-wide association studies (GWAS). However, the large number of SNPs ha...
Background: In population-based studies, it is generally recognized that single nucleotide polymorphism (SNP) markers are not independent. Rather, they are carried by haplotypes, ...
Background: Haplotype analysis has gained increasing attention in the context of association studies of disease genes and drug responsivities over the last years. The potential us...
Background: With the advent of cost-effective genotyping technologies, genome-wide association studies allow researchers to examine hundreds of thousands of single nucleotide poly...
Background: Millions of single nucleotide polymorphisms have been identified as a result of the human genome project and the rapid advance of high throughput genotyping technology...
Wei Yu, Anja Wulf, Tiebin Liu, Muin J. Khoury, Mar...