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BMCBI
2010
108views more  BMCBI 2010»
13 years 5 months ago
Confronting two-pair primer design for enzyme-free SNP genotyping based on a genetic algorithm
Background: Polymerase chain reaction with confronting two-pair primers (PCR-CTPP) method produces allelespecific DNA bands of different lengths by adding four designed primers an...
Cheng-Hong Yang, Yu-Huei Cheng, Li-Yeh Chuang, Hsu...
BMCBI
2010
100views more  BMCBI 2010»
13 years 5 months ago
Partitioning of copy-number genotypes in pedigrees
Background: Copy number variations (CNVs) and polymorphisms (CNPs) have only recently gained the genetic community's attention. Conservative estimates have shown that CNVs an...
Louis-Philippe Lemieux Perreault, Gregor U. Andelf...
RECOMB
2003
Springer
14 years 6 months ago
Towards optimally multiplexed applications of universal DNA tag systems
We study a design and optimization problem that occurs, for example, when single nucleotide polymorphisms (SNPs) are to be genotyped using a universal DNA tag array. The problem o...
Amir Ben-Dor, Tzvika Hartman, Benno Schwikowski, R...
BMCBI
2007
77views more  BMCBI 2007»
13 years 5 months ago
Effective selection of informative SNPs and classification on the HapMap genotype data
Background: Since the single nucleotide polymorphisms (SNPs) are genetic variations which determine the difference between any two unrelated individuals, the SNPs can be used to i...
Nina Zhou, Lipo Wang
NAR
2011
216views Computer Vision» more  NAR 2011»
12 years 8 months ago
dbDNV: a resource of duplicated gene nucleotide variants in human genome
Gene duplications are scattered widely throughout the human genome. A single-base difference located in nearly identical duplicated segments may be misjudged as a single nucleotid...
Meng-Ru Ho, Kuo-Wang Tsai, Chun-houh Chen, Wen-cha...