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EDBT
2012
ACM
257views Database» more  EDBT 2012»
11 years 7 months ago
Indexing and mining topological patterns for drug discovery
Increased availability of large repositories of chemical compounds has created new challenges and opportunities for the application of data-mining and indexing techniques to probl...
Sayan Ranu, Ambuj K. Singh
WWW
2007
ACM
14 years 5 months ago
A new suffix tree similarity measure for document clustering
In this paper, we propose a new similarity measure to compute the pairwise similarity of text-based documents based on suffix tree document model. By applying the new suffix tree ...
Hung Chim, Xiaotie Deng
BMCBI
2005
100views more  BMCBI 2005»
13 years 5 months ago
EvDTree: structure-dependent substitution profiles based on decision tree classification of 3D environments
Background: Structure-dependent substitution matrices increase the accuracy of sequence alignments when the 3D structure of one sequence is known, and are successful e.g. in fold ...
Jean-Christophe Gelly, Laurent Chiche, Jér&...
RECOMB
1999
Springer
13 years 9 months ago
Fast detection of common geometric substructure in proteins
We consider the problem of identifying common three-dimensional substructures between proteins. Our method is based on comparing the shape of the α-carbon backbone structures of ...
L. Paul Chew, Daniel P. Huttenlocher, Klara Kedem,...
BMCBI
2007
128views more  BMCBI 2007»
13 years 5 months ago
A robust and efficient algorithm for the shape description of protein structures and its application in predicting ligand bindin
Background: An accurate description of protein shape derived from protein structure is necessary to establish an understanding of protein-ligand interactions, which in turn will l...
Lei Xie, Philip E. Bourne