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CSB
2003
IEEE
13 years 10 months ago
Haplotype Motifs: An Algorithmic Approach to Locating Evolutionarily Conserved Patterns in Haploid Sequences
The promise of plentiful data on common human genetic variations has given hope that we will be able to uncover genetic factors behind common diseases that have proven difficult ...
Russell Schwartz
CSB
2004
IEEE
158views Bioinformatics» more  CSB 2004»
13 years 8 months ago
Algorithms for Association Study Design Using a Generalized Model of Haplotype Conservation
There is considerable interest in computational methods to assist in the use of genetic polymorphism data for locating disease-related genes. Haplotypes, contiguous sets of correl...
Russell Schwartz
BMCBI
2006
87views more  BMCBI 2006»
13 years 4 months ago
Phylogeny based discovery of regulatory elements
Background: Algorithms that locate evolutionarily conserved sequences have become powerful tools for finding functional DNA elements, including transcription factor binding sites;...
Jason Gertz, Justin C. Fay, Barak A. Cohen