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» Hardware-Accelerated RNA Secondary-Structure Alignment
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COMPLIFE
2005
Springer
13 years 11 months ago
Fast and Accurate Structural RNA Alignment by Progressive Lagrangian Optimization
During the last few years new functionalities of RNA have been discovered, renewing the need for computational tools for their analysis. To this respect, multiple sequence alignmen...
Markus Bauer, Gunnar W. Klau, Knut Reinert
CORR
2006
Springer
159views Education» more  CORR 2006»
13 years 5 months ago
Structural Alignments of pseudo-knotted RNA-molecules in polynomial time
An RNA molecule is structured on several layers. The primary and most obvious structure is its sequence of bases, i.e. a word over the alphabet {A, C, G, U}. The higher structure i...
Michael Brinkmeier
WABI
2005
Springer
120views Bioinformatics» more  WABI 2005»
13 years 11 months ago
Multiple Structural RNA Alignment with Lagrangian Relaxation
In contrast to proteins, many classes of functionally related RNA molecules show a rather weak sequence conservation but instead a fairly well conserved secondary structure. Hence ...
Markus Bauer, Gunnar W. Klau, Knut Reinert
TCBB
2010
114views more  TCBB 2010»
13 years 4 months ago
Cache-Oblivious Dynamic Programming for Bioinformatics
— We present efficient cache-oblivious algorithms for some well-studied string problems in bioinformatics including the longest common subsequence, global pairwise sequence alig...
Rezaul Alam Chowdhury, Hai-son Le, Vijaya Ramachan...
BMCBI
2007
226views more  BMCBI 2007»
13 years 5 months ago
MiRFinder: an improved approach and software implementation for genome-wide fast microRNA precursor scans
Background: MicroRNAs (miRNAs) are recognized as one of the most important families of noncoding RNAs that serve as important sequence-specific post-transcriptional regulators of ...
Ting-Hua Huang, Bin Fan, Max F. Rothschild, Zhi-Li...