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» Hardware-Accelerated RNA Secondary-Structure Alignment
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BMCBI
2002
108views more  BMCBI 2002»
13 years 5 months ago
A memory-efficient dynamic programming algorithm for optimal alignment of a sequence to an RNA secondary structure
Background: Covariance models (CMs) are probabilistic models of RNA secondary structure, analogous to profile hidden Markov models of linear sequence. The dynamic programming algo...
Sean R. Eddy
RECOMB
2005
Springer
14 years 5 months ago
Consensus Folding of Unaligned RNA Sequences Revisited
As one of the earliest problems in computational biology, RNA secondary structure prediction (sometimes referred to as "RNA folding") problem has attracted attention agai...
Vineet Bafna, Haixu Tang, Shaojie Zhang
BMCBI
2011
13 years 9 days ago
R2R - software to speed the depiction of aesthetic consensus RNA secondary structures
Background: With continuing identification of novel structured noncoding RNAs, there is an increasing need to create schematic diagrams showing the consensus features of these mol...
Zasha Weinberg, Ronald R. Breaker
BIOSURVEILLANCE
2007
Springer
13 years 11 months ago
Detecting Conserved RNA Secondary Structures in Viral Genomes: The RADAR Approach
Abstract. Conserved regions, or motifs, present among RNA secondary structures serve as a useful indicator for predicting the functionality of the RNA molecules. Automated detectio...
Mugdha Khaladkar, Jason T. L. Wang
BMCBI
2006
130views more  BMCBI 2006»
13 years 5 months ago
4SALE - A tool for synchronous RNA sequence and secondary structure alignment and editing
Background: In sequence analysis the multiple alignment builds the fundament of all proceeding analyses. Errors in an alignment could strongly influence all succeeding analyses an...
Philipp N. Seibel, Tobias Müller, Thomas Dand...