Abstract. A hidden Markov model is introduced for descriptive modelling the mosaic–like structures of haplotypes, due to iterated recombinations within a population. Methods usin...
Mikko Koivisto, Teemu Kivioja, Heikki Mannila, Pas...
We give a new algorithm for the genotype phasing problem. Our solution is based on a hidden Markov model for haplotypes. The model has a uniform structure, unlike most solutions pr...
Pasi Rastas, Mikko Koivisto, Heikki Mannila, Esko ...
Abstract. Genome sequencing will soon produce haplotype data for individuals. For pedigrees of related individuals, sequencing appears to be an attractive alternative to genotyping...
In the last years haplotype reconstruction and haplotype blocks discovery, i.e., the estimation of patterns of linkage disequilibrium (LD) in the haplotypes, riveted the attention ...
Alessandro Perina, Marco Cristani, Giovanni Malerb...