Background: Quantitative simultaneous monitoring of the expression levels of thousands of genes under various experimental conditions is now possible using microarray experiments....
Abstract. The computational genome-wide annotation of gene functions requires the prediction of hierarchically structured functional classes and can be formalized as a multiclass, ...
The soundness of clustering in the analysis of gene expression profiles and gene function prediction is based on the hypothesis that genes with similar expression profiles may imp...
Background: A new paradigm of biological investigation takes advantage of technologies that produce large high throughput datasets, including genome sequences, interactions of pro...
Abstract. This paper proposes a novel Ant Colony Optimisation algorithm for the hierarchical problem of predicting protein functions using the Gene Ontology (GO). The GO structure ...
Fernando E. B. Otero, Alex Alves Freitas, Colin G....