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» Homology Detection via Family Pairwise Search
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BMCBI
2005
119views more  BMCBI 2005»
13 years 5 months ago
The distance-profile representation and its application to detection of distantly related protein families
Background: Detecting homology between remotely related protein families is an important problem in computational biology since the biological properties of uncharacterized protei...
Chin-Jen Ku, Golan Yona
BMCBI
2008
91views more  BMCBI 2008»
13 years 5 months ago
t2prhd: a tool to study the patterns of repeat evolution
Background: The models developed to characterize the evolution of multigene families (such as the birth-and-death and the concerted models) have also been applied on the level of ...
Botond Sipos, Kálmán Somogyi, Istv&a...
BMCBI
2007
102views more  BMCBI 2007»
13 years 5 months ago
Identification of homologs in insignificant blast hits by exploiting extrinsic gene properties
Background: Homology is a key concept in both evolutionary biology and genomics. Detection of homology is crucial in fields like the functional annotation of protein sequences and...
Jos Boekhorst, Berend Snel
RECOMB
1999
Springer
13 years 9 months ago
Classifying proteins by family using the product of correlated p-values
An important goal in bioinformatics is determining the homology and function of proteins from their sequences. Pairwise sequence similarity algorithms are often employed for this ...
Timothy L. Bailey, William Noble Grundy
HICSS
1994
IEEE
157views Biometrics» more  HICSS 1994»
13 years 9 months ago
A Protein Family Classification Method for Analysis of Large DNA Sequences
A method is described for identification and classification of proteins encoded in large DNA sequences. Previously, an automated system was introduced for the general detection of...
Steven Henikoff, Jorja G. Henikoff