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BIOCOMP
2006
13 years 6 months ago
Identification of Intrinsically Unstructured Regions in Proteins Using Primary Structure
Most proteins function only when folded into a particular 3D configuration. Recently, a class of proteins has been discovered that do not fold into any particular configuration; t...
Mary Qu Yang, Jack Y. Yang
BIRD
2007
Springer
117views Bioinformatics» more  BIRD 2007»
13 years 11 months ago
Enhancing Protein Disorder Detection by Refined Secondary Structure Prediction
More and more proteins have been observed to display functions through intrinsic disorder. Such structurally flexible regions are shown to play important roles in biological proces...
Chung-Tsai Su, Tong-Ming Hsu, Chien-Yu Chen, Yu-Ye...
BMCBI
2010
176views more  BMCBI 2010»
13 years 5 months ago
Bayesian statistical modelling of human protein interaction network incorporating protein disorder information
Background: We present a statistical method of analysis of biological networks based on the exponential random graph model, namely p2-model, as opposed to previous descriptive app...
Svetlana Bulashevska, Alla Bulashevska, Roland Eil...
BMCBI
2007
102views more  BMCBI 2007»
13 years 5 months ago
Identification of homologs in insignificant blast hits by exploiting extrinsic gene properties
Background: Homology is a key concept in both evolutionary biology and genomics. Detection of homology is crucial in fields like the functional annotation of protein sequences and...
Jos Boekhorst, Berend Snel
BMCBI
2010
89views more  BMCBI 2010»
13 years 5 months ago
Semi-automatic identification of punching areas for tissue microarray building: the tubular breast cancer pilot study
Background: Tissue MicroArray technology aims to perform immunohistochemical staining on hundreds of different tissue samples simultaneously. It allows faster analysis, considerab...
Federica Viti, Ivan Merelli, Mieke Timmermans, Mic...