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BMCBI
2006
109views more  BMCBI 2006»
13 years 5 months ago
An integrated system for genetic analysis
Background: Large-scale genetic mapping projects require data management systems that can handle complex phenotypes and detect and correct high-throughput genotyping errors, yet a...
Simon Fiddy, David Cattermole, Dong Xie, Xiao Yuan...
ALGORITHMICA
1999
84views more  ALGORITHMICA 1999»
13 years 4 months ago
Computational Approaches to Drug Design
Abstract. The rational approach to pharmaceutical drug design begins with an investigation of the relationship between chemical structure and biological activity. Information gaine...
Paul W. Finn, Lydia E. Kavraki
BMCBI
2002
214views more  BMCBI 2002»
13 years 4 months ago
Automated modelling of signal transduction networks
Background: Intracellular signal transduction is achieved by networks of proteins and small molecules that transmit information from the cell surface to the nucleus, where they ul...
Martin Steffen, Allegra Petti, John Aach, Patrik D...
BMCBI
2005
132views more  BMCBI 2005»
13 years 5 months ago
Kalign - an accurate and fast multiple sequence alignment algorithm
Background: The alignment of multiple protein sequences is a fundamental step in the analysis of biological data. It has traditionally been applied to analyzing protein families f...
Timo Lassmann, Erik L. L. Sonnhammer
GEOINFORMATICA
2007
223views more  GEOINFORMATICA 2007»
13 years 5 months ago
Algorithms for Nearest Neighbor Search on Moving Object Trajectories
Nearest Neighbor (NN) search has been in the core of spatial and spatiotemporal database research during the last decade. The literature on NN query processing algorithms so far d...
Elias Frentzos, Kostas Gratsias, Nikos Pelekis, Ya...