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BMCBI
2005
136views more  BMCBI 2005»
13 years 4 months ago
Identification of clustered microRNAs using an ab initio prediction method
Background: MicroRNAs (miRNAs) are endogenous 21 to 23-nucleotide RNA molecules that regulate protein-coding gene expression in plants and animals via the RNA interference pathway...
Alain Sewer, Nicodème Paul, Pablo Landgraf,...
BMCBI
2007
165views more  BMCBI 2007»
13 years 4 months ago
Ab initio identification of human microRNAs based on structure motifs
Background: MicroRNAs (miRNAs) are short, non-coding RNA molecules that are directly involved in post-transcriptional regulation of gene expression. The mature miRNA sequence bind...
Markus Brameier, Carsten Wiuf
BMCBI
2010
99views more  BMCBI 2010»
13 years 5 months ago
Prediction of novel precursor miRNAs using a context-sensitive hidden Markov model (CSHMM)
Background: It has been apparent in the last few years that small non coding RNAs (ncRNA) play a very significant role in biological regulation. Among these microRNAs (miRNAs), 22...
Sumeet Agarwal, Candida Vaz, Alok Bhattacharya, As...
BMCBI
2010
175views more  BMCBI 2010»
13 years 5 months ago
Calibur: a tool for clustering large numbers of protein decoys
Background: Ab initio protein structure prediction methods generate numerous structural candidates, which are referred to as decoys. The decoy with the most number of neighbors of...
Shuai Cheng Li, Yen Kaow Ng
BMCBI
2008
135views more  BMCBI 2008»
13 years 5 months ago
Functional site prediction selects correct protein models
Background: The prediction of protein structure can be facilitated by the use of constraints based on a knowledge of functional sites. Without this information it is still possibl...
Vijayalakshmi Chelliah, William R. Taylor