Sciweavers

9 search results - page 1 / 2
» Identification of deleterious non-synonymous single nucleoti...
Sort
View
BMCBI
2008
87views more  BMCBI 2008»
13 years 5 months ago
Identification of deleterious non-synonymous single nucleotide polymorphisms using sequence-derived information
Background: As the number of non-synonymous single nucleotide polymorphisms (nsSNPs), also known as single amino acid polymorphisms (SAPs), increases rapidly, computational method...
Jing Hu, Changhui Yan
BMCBI
2007
127views more  BMCBI 2007»
13 years 4 months ago
Predicting the phenotypic effects of non-synonymous single nucleotide polymorphisms based on support vector machines
Background: Human genetic variations primarily result from single nucleotide polymorphisms (SNPs) that occur approximately every 1000 bases in the overall human population. The no...
Jian Tian, Ningfeng Wu, Xuexia Guo, Jun Guo, Juhua...
BMCBI
2008
151views more  BMCBI 2008»
13 years 5 months ago
An integrated database-pipeline system for studying single nucleotide polymorphisms and diseases
Background: Studies on the relationship between disease and genetic variations such as single nucleotide polymorphisms (SNPs) are important. Genetic variations can cause disease b...
Jin Ok Yang, Sohyun Hwang, Jeongsu Oh, Jong Bhak, ...
BMCBI
2008
88views more  BMCBI 2008»
13 years 5 months ago
Large-scale identification of polymorphic microsatellites using an in silico approach
Background: Simple Sequence Repeat (SSR) or microsatellite markers are valuable for genetic research. Experimental methods to develop SSR markers are laborious, time consuming and...
Jifeng Tang, Samantha J. Baldwin, Jeanne M. E. Jac...
BMCBI
2007
145views more  BMCBI 2007»
13 years 5 months ago
Genome bioinformatic analysis of nonsynonymous SNPs
Background: Genome-wide association studies of common diseases for common, low penetrance causal variants are underway. A proportion of these will alter protein sequences, the mos...
David F. Burke, Catherine L. Worth, Eva-Maria Prie...