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» Identifying Binding Sites in Sequential Genomic Data
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BMCBI
2007
156views more  BMCBI 2007»
13 years 6 months ago
Large-scale clustering of CAGE tag expression data
Background: Recent analyses have suggested that many genes possess multiple transcription start sites (TSSs) that are differentially utilized in different tissues and cell lines. ...
Kazuro Shimokawa, Yuko Okamura-Oho, Takio Kurita, ...
BIBE
2007
IEEE
114views Bioinformatics» more  BIBE 2007»
14 years 11 days ago
A Hierarchical Grow-and-Match Algorithm for Backbone Resonance Assignments Given 3D Structure
Abstract—This paper develops an algorithm for NMR backbone resonance assignment given a 3D structure and a set of relatively sparse 15 N-edited NMR data, with the through-space 1...
Fei Xiong, Chris Bailey-Kellogg
BMCBI
2010
145views more  BMCBI 2010»
13 years 6 months ago
JCoDA: a tool for detecting evolutionary selection
Background: The incorporation of annotated sequence information from multiple related species in commonly used databases (Ensembl, Flybase, Saccharomyces Genome Database, Wormbase...
Steven N. Steinway, Ruth Dannenfelser, Christopher...
GECCO
2007
Springer
258views Optimization» more  GECCO 2007»
13 years 10 months ago
TFBS identification by position- and consensus-led genetic algorithm with local filtering
Identification of Transcription Factor Binding Site (TFBS) motifs in multiple DNA upstream sequences is important in understanding the mechanism of gene regulation. This identific...
Tak-Ming Chan, Kwong-Sak Leung, Kin-Hong Lee
BMCBI
2010
123views more  BMCBI 2010»
13 years 1 months ago
Predicting conserved protein motifs with Sub-HMMs
Background: Profile HMMs (hidden Markov models) provide effective methods for modeling the conserved regions of protein families. A limitation of the resulting domain models is th...
Kevin Horan, Christian R. Shelton, Thomas Girke