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BMCBI
2010
95views more  BMCBI 2010»
13 years 5 months ago
Identifying main effects and epistatic interactions from large-scale SNP data via adaptive group Lasso
Background: Single nucleotide polymorphism (SNP) based association studies aim at identifying SNPs associated with phenotypes, for example, complex diseases. The associated SNPs m...
Can Yang, Xiang Wan, Qiang Yang, Hong Xue, Weichua...
BMCBI
2010
136views more  BMCBI 2010»
13 years 5 months ago
Protein structure analysis of mutations causing inheritable diseases. An e-Science approach with life scientist friendly interfa
Background: Many newly detected point mutations are located in protein-coding regions of the human genome. Knowledge of their effects on the protein's 3D structure provides i...
Hanka Venselaar, Tim A. H. te Beek, Remko K. P. Ku...
ASPDAC
2008
ACM
169views Hardware» more  ASPDAC 2008»
13 years 7 months ago
Analytical model for the impact of multiple input switching noise on timing
The timing models used in current Static Timing Analysis tools use gate delays only for single input switching events. It is well known that the temporal proximity of signals arriv...
Rajeshwary Tayade, Sani R. Nassif, Jacob A. Abraha...
CEC
2005
IEEE
13 years 10 months ago
Investigating the effect of random noise on the evolution of colour terms
Abstract- The effect of adding noise to an expressioninduction model of language evolution was investigated. The model consisted of a number of artificial people who were able to i...
Mike Dowman
BMCBI
2011
13 years 6 days ago
Identifying hypermethylated CpG islands using a quantile regression model
Background: DNA methylation has been shown to play an important role in the silencing of tumor suppressor genes in various tumor types. In order to have a system-wide understandin...
Shuying Sun, Zhengyi Chen, Pearlly Yan, Yi-Wen Hua...