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BMCBI
2010
151views more  BMCBI 2010»
13 years 5 months ago
TF-finder: A software package for identifying transcription factors involved in biological processes using microarray data and e
Background: Identification of transcription factors (TFs) involved in a biological process is the first step towards a better understanding of the underlying regulatory mechanisms...
Xiaoqi Cui, Tong Wang, Huann-Sheng Chen, Victor Bu...
BMCBI
2010
100views more  BMCBI 2010»
13 years 5 months ago
Trimming of mammalian transcriptional networks using network component analysis
Background: Network Component Analysis (NCA) has been used to deduce the activities of transcription factors (TFs) from gene expression data and the TF-gene binding relationship. ...
Linh M. Tran, Daniel R. Hyduke, James C. Liao
TCS
2008
13 years 5 months ago
Temporal constraints in the logical analysis of regulatory networks
Starting from the logical description of gene regulatory networks developed by R. Thomas, we introduce an enhanced modelling approach based on timed automata. We obtain a refined ...
Heike Siebert, Alexander Bockmayr
DSS
2007
127views more  DSS 2007»
13 years 5 months ago
Large-scale regulatory network analysis from microarray data: modified Bayesian network learning and association rule mining
We present two algorithms for learning large-scale gene regulatory networks from microarray data: a modified informationtheory-based Bayesian network algorithm and a modified asso...
Zan Huang, Jiexun Li, Hua Su, George S. Watts, Hsi...
BMCBI
2010
144views more  BMCBI 2010»
13 years 5 months ago
Identifying overrepresented concepts in gene lists from literature: a statistical approach based on Poisson mixture model
Background: Large-scale genomic studies often identify large gene lists, for example, the genes sharing the same expression patterns. The interpretation of these gene lists is gen...
Xin He, Moushumi Sen Sarma, Xu Ling, Brant W. Chee...