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» Identifying biochemical reaction networks from heterogeneous...
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BMCBI
2008
160views more  BMCBI 2008»
13 years 5 months ago
Predicting cancer involvement of genes from heterogeneous data
Background: Systematic approaches for identifying proteins involved in different types of cancer are needed. Experimental techniques such as microarrays are being used to characte...
Ramon Aragues, Chris Sander, Baldo Oliva
BMCBI
2010
202views more  BMCBI 2010»
13 years 5 months ago
NeMo: Network Module identification in Cytoscape
Background: As the size of the known human interactome grows, biologists increasingly rely on computational tools to identify patterns that represent protein complexes and pathway...
Corban G. Rivera, Rachit Vakil, Joel S. Bader
BIBE
2008
IEEE
160views Bioinformatics» more  BIBE 2008»
13 years 11 months ago
Parallel integration of heterogeneous genome-wide data sources
— Heterogeneous genome-wide data sources capture information on various aspects of complex biological systems. For instance, transcriptome, interactome and phenome-level informat...
Derek Greene, Kenneth Bryan, Padraig Cunningham
BMCBI
2007
179views more  BMCBI 2007»
13 years 5 months ago
Automated smoother for the numerical decoupling of dynamics models
Background: Structure identification of dynamic models for complex biological systems is the cornerstone of their reverse engineering. Biochemical Systems Theory (BST) offers a pa...
Marco Vilela, Carlos Cristiano H. Borges, Susana V...
BMCBI
2005
169views more  BMCBI 2005»
13 years 4 months ago
Genetic interaction motif finding by expectation maximization - a novel statistical model for inferring gene modules from synthe
Background: Synthetic lethality experiments identify pairs of genes with complementary function. More direct functional associations (for example greater probability of membership...
Yan Qi 0003, Ping Ye, Joel S. Bader