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CORR
2007
Springer
100views Education» more  CORR 2007»
13 years 4 months ago
Identifying statistical dependence in genomic sequences via mutual information estimates
Questions of understanding and quantifying the representation and amount of information in organisms have become a central part of biological research, as they potentially hold th...
H. M. Aktulga, I. Kontoyiannis, L. A. Lyznik, Luka...
BMCBI
2008
132views more  BMCBI 2008»
13 years 5 months ago
The Average Mutual Information Profile as a Genomic Signature
Background: Occult organizational structures in DNA sequences may hold the key to understanding functional and evolutionary aspects of the DNA molecule. Such structures can also p...
Mark Bauer, Sheldon M. Schuster, Khalid Sayood
INFORMATICALT
2010
142views more  INFORMATICALT 2010»
13 years 3 months ago
Complexity Estimation of Genetic Sequences Using Information-Theoretic and Frequency Analysis Methods
The genetic information in cells is stored in DNA sequences, represented by a string of four letters, each corresponding to a definite type of nucleotides. Genomic DNA sequences a...
Robertas Damasevicius
ALMOB
2008
131views more  ALMOB 2008»
13 years 5 months ago
Fast algorithms for computing sequence distances by exhaustive substring composition
The increasing throughput of sequencing raises growing needs for methods of sequence analysis and comparison on a genomic scale, notably, in connection with phylogenetic tree reco...
Alberto Apostolico, Olgert Denas
BIBM
2010
IEEE
151views Bioinformatics» more  BIBM 2010»
13 years 3 months ago
Probabilistic topic modeling for genomic data interpretation
Recently, the concept of a species containing both core and distributed genes, known as the supra- or pangenome theory, has been introduced. In this paper, we aim to develop a new ...
Xin Chen, Xiaohua Hu, Xiajiong Shen, Gail Rosen