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CIBCB
2007
IEEE
13 years 10 months ago
Prediction of Enzyme Catalytic Sites from Sequence Using Neural Networks
The accurate prediction of enzyme catalytic sites remains an open problem in bioinformatics. Recently, several structure-based methods have become popular; however, few robust seq...
Swati Pande, Amar Raheja, Dennis R. Livesay
BMCBI
2007
142views more  BMCBI 2007»
13 years 6 months ago
Improving model construction of profile HMMs for remote homology detection through structural alignment
Background: Remote homology detection is a challenging problem in Bioinformatics. Arguably, profile Hidden Markov Models (pHMMs) are one of the most successful approaches in addre...
Juliana S. Bernardes, Alberto M. R. Dávila,...