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» Improved comparison of protein subcellular location patterns
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ISBI
2006
IEEE
14 years 5 months ago
Improved comparison of protein subcellular location patterns
* A common task in cell and molecular biology is to evaluate the difference or similarity among location patterns under different circumstances. Our previous work has described an...
Ting Zhao, Stalia Soto, Robert F. Murphy
ISBI
2004
IEEE
14 years 5 months ago
Automated Interpretation of Subcellular Location Patterns
Fluorescence microscopy is widely used to analyze the distribution of proteins within cells. As currently practiced, the assignment of a protein to a particular organelle is done ...
Robert F. Murphy
BMCBI
2004
176views more  BMCBI 2004»
13 years 4 months ago
Boosting accuracy of automated classification of fluorescence microscope images for location proteomics
Background: Detailed knowledge of the subcellular location of each expressed protein is critical to a full understanding of its function. Fluorescence microscopy, in combination w...
Kai Huang, Robert F. Murphy
ISMB
2000
13 years 6 months ago
Towards a Systematics for Protein Subcellular Location: Quantitative Description of Protein Localization Patterns and Automated
Determination of the functions of all expressed proteins represents one of the major upcoming challenges in computational molecular biology. Since subcellular location plays a cru...
Robert F. Murphy, Michael V. Boland, Meel Velliste
ISBI
2008
IEEE
14 years 5 months ago
Automated comparison of protein subcellular location patterns between images of normal and cancerous tissues
Early cancer diagnosis and evaluation of cancer progression during treatment are two important factors for clinical therapy. In this study we propose a novel approach which automa...
Estelle Glory, Justin Newberg, Robert F. Murphy