Background: Many newly detected point mutations are located in protein-coding regions of the human genome. Knowledge of their effects on the protein's 3D structure provides i...
Hanka Venselaar, Tim A. H. te Beek, Remko K. P. Ku...
We present a method for identifying connected gene subnetworks significantly enriched for genes that are dysregulated in specimens of a disease. These subnetworks provide a signat...
Monitoring the dynamics of networks in the brain is of central importance in normal and disease states. Current methods of detecting networks in the recorded EEG such as correlati...
Pamela Wen-Hsin Lee, Z. Jane Wang, Martin J. McKeo...
Effective diagnosis of Alzheimer's disease (AD) is of primary importance in biomedical research. Recent studies have demonstrated that neuroimaging parameters are sensitive a...
Jieping Ye, Kewei Chen, Teresa Wu, Jing Li, Zheng ...
The availability of high density single nucleotide polymorphisms (SNPs) data has made genome-wide association study computationally challenging. Twolocus epistasis (gene-gene inter...