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» Improving Operon Prediction in E. coli
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CSB
2005
IEEE
118views Bioinformatics» more  CSB 2005»
13 years 11 months ago
Gene Teams with Relaxed Proximity Constraint
Functionally related genes co-evolve, probably due to the strong selection pressure in evolution. Thus we expect that they are present in multiple genomes. Physical proximity amon...
Sun Kim, Jeong-Hyeon Choi, Jiong Yang
BMCBI
2007
86views more  BMCBI 2007»
13 years 6 months ago
Toxicogenomic analysis incorporating operon-transcriptional coupling and toxicant concentration-expression response: analysis of
Background: Deficiencies in microarray technology cause unwanted variation in the hybridization signal, obscuring the true measurements of intracellular transcript levels. Here we...
William O. Ward, Carol D. Swartz, Steffen Porwolli...
BMCBI
2006
118views more  BMCBI 2006»
13 years 6 months ago
Low degree metabolites explain essential reactions and enhance modularity in biological networks
Background: Recently there has been a lot of interest in identifying modules at the level of genetic and metabolic networks of organisms, as well as in identifying single genes an...
Areejit Samal, Shalini Singh, Varun Giri, Sandeep ...
BMCBI
2006
74views more  BMCBI 2006»
13 years 6 months ago
An unsupervised classification scheme for improving predictions of prokaryotic TIS
Background: Although it is not difficult for state-of-the-art gene finders to identify coding regions in prokaryotic genomes, exact prediction of the corresponding translation ini...
Maike Tech, Peter Meinicke
BMCBI
2007
144views more  BMCBI 2007»
13 years 6 months ago
InPrePPI: an integrated evaluation method based on genomic context for predicting protein-protein interactions in prokaryotic ge
Background: Although many genomic features have been used in the prediction of proteinprotein interactions (PPIs), frequently only one is used in a computational method. After rea...
Jingchun Sun, Yan Sun, Guohui Ding, Qi Liu, Chuan ...