7 search results - page 1 / 2 » Improving Remote Homology Detection Using Sequence Propertie... |
BIOCOMP
2009
2009
Improving Remote Homology Detection Using Sequence Properties and Position Specific Scoring Matrices
13 years 5 months ago
Current biological sequence comparison tools frequently fail to recognize matches between homologs when sequence similarity is below the twilight zone of less than 25% sequence id...
BMCBI
2008
13 years 4 months ago
2008
Background: Nonnegative matrix factorization (NMF) is a feature extraction method that has the property of intuitive part-based representation of the original features. This uniqu...
BMCBI
2005
13 years 4 months ago
2005
Background: Detecting homology between remotely related protein families is an important problem in computational biology since the biological properties of uncharacterized protei...
BMCBI
2010
13 years 4 months ago
2010
Background: The study of protein-small molecule interactions is vital for understanding protein function and for practical applications in drug discovery. To benefit from the rapi...
BMCBI
2006
13 years 4 months ago
2006
Background: More and more disordered regions have been discovered in protein sequences, and many of them are found to be functionally significant. Previous studies reveal that dis...